Carol Ann Susi, the veteran character actress who voiced Mrs. Wolowitz, Howard’s mother, on The Big Bang Theory died after a short fight with cancer. She was 62 years-old.

“The Big Bang Theory family has lost a beloved member today with the passing of Carol Ann Susi, who hilariously and memorably voiced the role of Mrs. Wolowitz,” CBS, Warner Bros. Television and The Big Bang Theory executive producers Chuck Lorre, Steven Molaro and Bill Prady said in a statement. “Unseen by viewers, the Mrs. Wolowitz character became a bit of a mystery throughout the show’s eight seasons. What was not a mystery, however, was Carol Ann’s immense talent and comedic timing, which were on display during each unforgettable appearance. In addition to her talent, Carol Ann was a constant source of joy and kindness to all. Our thoughts and deepest condolences are with her family during this time, and we will miss her greatly.”

They explained further that it is too soon to decide how to proceed with the show, whether to replace Susi or have the character die too.

The feisty Italian from Brooklyn studied acting at HB Studio in New York and moved to Los Angeles in the 1970s. She appeared as Monique Marmelstein the secretary on Kolchak: The Night Stalker as well as in Cheers, Doogie Howser, M.D., Growing Pains, Night Court, ER, Married with Children, Mad About You, Just Shoot Me, The King of Queens, and Six Feet Under. One of her most well-known guest spots was on Seinfeld in “The Boyfriend” two-parter when she dates George after he spots a picture of her on her mother’s desk at the unemployment office. On film she was in Wedding Band, My Blue Heaven, Death Becomes Her, Eat Your Heart Out, Cats & Dogs, and Just Go with It. She also worked on stage in the original production of Ladies’ Room, as well as Heartbreak Help and Coyote Women.